PhytophthoraV1, Main, Exploration, bibRecord, 000899

The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein.

Identifieur interne : 000899 ( Main/Exploration ); précédent : 000898; suivant : 000900

The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein.

Auteurs : Jordi Gamir [Suisse] ; Rabih Darwiche [Suisse] ; Pieter Van'T Hof [Suisse] ; Vineet Choudhary [Suisse] ; Michael Stumpe [Suisse] ; Roger Schneiter [Suisse] ; Felix Mauch [Suisse]

Source :

The Plant journal : for cell and molecular biology [ 1365-313X ] ; 2017.

RBID : pubmed:27747953

Descripteurs français

English descriptors

KwdEn :
- Anti-Infective Agents (metabolism), Cholesterol (metabolism), Disease Resistance (genetics), Gene Expression Regulation, Plant (MeSH), Host-Pathogen Interactions (MeSH), Immunoblotting (MeSH), Lycopersicon esculentum (genetics), Lycopersicon esculentum (metabolism), Lycopersicon esculentum (microbiology), Phytophthora (physiology), Plant Diseases (genetics), Plant Diseases (microbiology), Plant Proteins (genetics), Plant Proteins (metabolism), Plants (genetics), Plants (metabolism), Plants (microbiology), Protein Binding (MeSH), Sterols (metabolism), Tobacco (genetics), Tobacco (metabolism), Tobacco (microbiology).
MESH :
- chemical , genetics : Plant Proteins.
- chemical , metabolism : Anti-Infective Agents, Cholesterol, Plant Proteins, Sterols.
- genetics : Disease Resistance, Lycopersicon esculentum, Plant Diseases, Plants, Tobacco.
- metabolism : Lycopersicon esculentum, Plants, Tobacco.
- microbiology : Lycopersicon esculentum, Plant Diseases, Plants, Tobacco.
- physiology : Phytophthora.
- Gene Expression Regulation, Plant, Host-Pathogen Interactions, Immunoblotting, Protein Binding.

Abstract

Pathogenesis-related proteins played a pioneering role 50 years ago in the discovery of plant innate immunity as a set of proteins that accumulated upon pathogen challenge. The most abundant of these proteins, PATHOGENESIS-RELATED 1 (PR-1) encodes a small antimicrobial protein that has become, as a marker of plant immune signaling, one of the most referred to plant proteins. The biochemical activity and mode of action of PR-1 proteins has remained elusive, however. Here, we provide genetic and biochemical evidence for the capacity of PR-1 proteins to bind sterols, and demonstrate that the inhibitory effect on pathogen growth is caused by the sequestration of sterol from pathogens. In support of our findings, sterol-auxotroph pathogens such as the oomycete Phytophthora are particularly sensitive to PR-1, whereas sterol-prototroph fungal pathogens become highly sensitive only when sterol biosynthesis is compromised. Our results are in line with previous findings showing that plants with enhanced PR-1 expression are particularly well protected against oomycete pathogens.

DOI: 10.1111/tpj.13398
PubMed: 27747953

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000B01
to stream Main, to step Curation: 000B01

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein.</title>
<author><name sortKey="Gamir, Jordi" sort="Gamir, Jordi" uniqKey="Gamir J" first="Jordi" last="Gamir">Jordi Gamir</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Darwiche, Rabih" sort="Darwiche, Rabih" uniqKey="Darwiche R" first="Rabih" last="Darwiche">Rabih Darwiche</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van T Hof, Pieter" sort="Van T Hof, Pieter" uniqKey="Van T Hof P" first="Pieter" last="Van'T Hof">Pieter Van'T Hof</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Choudhary, Vineet" sort="Choudhary, Vineet" uniqKey="Choudhary V" first="Vineet" last="Choudhary">Vineet Choudhary</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Stumpe, Michael" sort="Stumpe, Michael" uniqKey="Stumpe M" first="Michael" last="Stumpe">Michael Stumpe</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schneiter, Roger" sort="Schneiter, Roger" uniqKey="Schneiter R" first="Roger" last="Schneiter">Roger Schneiter</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mauch, Felix" sort="Mauch, Felix" uniqKey="Mauch F" first="Felix" last="Mauch">Felix Mauch</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:27747953</idno>
<idno type="pmid">27747953</idno>
<idno type="doi">10.1111/tpj.13398</idno>
<idno type="wicri:Area/Main/Corpus">000B01</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000B01</idno>
<idno type="wicri:Area/Main/Curation">000B01</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000B01</idno>
<idno type="wicri:Area/Main/Exploration">000B01</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein.</title>
<author><name sortKey="Gamir, Jordi" sort="Gamir, Jordi" uniqKey="Gamir J" first="Jordi" last="Gamir">Jordi Gamir</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Darwiche, Rabih" sort="Darwiche, Rabih" uniqKey="Darwiche R" first="Rabih" last="Darwiche">Rabih Darwiche</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Van T Hof, Pieter" sort="Van T Hof, Pieter" uniqKey="Van T Hof P" first="Pieter" last="Van'T Hof">Pieter Van'T Hof</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Choudhary, Vineet" sort="Choudhary, Vineet" uniqKey="Choudhary V" first="Vineet" last="Choudhary">Vineet Choudhary</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Stumpe, Michael" sort="Stumpe, Michael" uniqKey="Stumpe M" first="Michael" last="Stumpe">Michael Stumpe</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schneiter, Roger" sort="Schneiter, Roger" uniqKey="Schneiter R" first="Roger" last="Schneiter">Roger Schneiter</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mauch, Felix" sort="Mauch, Felix" uniqKey="Mauch F" first="Felix" last="Mauch">Felix Mauch</name>
<affiliation wicri:level="4"><nlm:affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Department of Biology, University of Fribourg, Fribourg</wicri:regionArea>
<orgName type="university">Université de Fribourg</orgName>
<placeName><settlement type="city">Fribourg</settlement>
<region nuts="3" type="region">Canton de Fribourg</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">The Plant journal : for cell and molecular biology</title>
<idno type="eISSN">1365-313X</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Infective Agents (metabolism)</term>
<term>Cholesterol (metabolism)</term>
<term>Disease Resistance (genetics)</term>
<term>Gene Expression Regulation, Plant (MeSH)</term>
<term>Host-Pathogen Interactions (MeSH)</term>
<term>Immunoblotting (MeSH)</term>
<term>Lycopersicon esculentum (genetics)</term>
<term>Lycopersicon esculentum (metabolism)</term>
<term>Lycopersicon esculentum (microbiology)</term>
<term>Phytophthora (physiology)</term>
<term>Plant Diseases (genetics)</term>
<term>Plant Diseases (microbiology)</term>
<term>Plant Proteins (genetics)</term>
<term>Plant Proteins (metabolism)</term>
<term>Plants (genetics)</term>
<term>Plants (metabolism)</term>
<term>Plants (microbiology)</term>
<term>Protein Binding (MeSH)</term>
<term>Sterols (metabolism)</term>
<term>Tobacco (genetics)</term>
<term>Tobacco (metabolism)</term>
<term>Tobacco (microbiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Anti-infectieux (métabolisme)</term>
<term>Cholestérol (métabolisme)</term>
<term>Immunotransfert (MeSH)</term>
<term>Interactions hôte-pathogène (MeSH)</term>
<term>Liaison aux protéines (MeSH)</term>
<term>Lycopersicon esculentum (génétique)</term>
<term>Lycopersicon esculentum (microbiologie)</term>
<term>Lycopersicon esculentum (métabolisme)</term>
<term>Maladies des plantes (génétique)</term>
<term>Maladies des plantes (microbiologie)</term>
<term>Phytophthora (physiologie)</term>
<term>Plantes (génétique)</term>
<term>Plantes (microbiologie)</term>
<term>Plantes (métabolisme)</term>
<term>Protéines végétales (génétique)</term>
<term>Protéines végétales (métabolisme)</term>
<term>Régulation de l'expression des gènes végétaux (MeSH)</term>
<term>Résistance à la maladie (génétique)</term>
<term>Stérols (métabolisme)</term>
<term>Tabac (génétique)</term>
<term>Tabac (microbiologie)</term>
<term>Tabac (métabolisme)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Plant Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Anti-Infective Agents</term>
<term>Cholesterol</term>
<term>Plant Proteins</term>
<term>Sterols</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Disease Resistance</term>
<term>Lycopersicon esculentum</term>
<term>Plant Diseases</term>
<term>Plants</term>
<term>Tobacco</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Lycopersicon esculentum</term>
<term>Maladies des plantes</term>
<term>Plantes</term>
<term>Protéines végétales</term>
<term>Résistance à la maladie</term>
<term>Tabac</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lycopersicon esculentum</term>
<term>Plants</term>
<term>Tobacco</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Lycopersicon esculentum</term>
<term>Maladies des plantes</term>
<term>Plantes</term>
<term>Tabac</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Lycopersicon esculentum</term>
<term>Plant Diseases</term>
<term>Plants</term>
<term>Tobacco</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Anti-infectieux</term>
<term>Cholestérol</term>
<term>Lycopersicon esculentum</term>
<term>Plantes</term>
<term>Protéines végétales</term>
<term>Stérols</term>
<term>Tabac</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Phytophthora</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Phytophthora</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Gene Expression Regulation, Plant</term>
<term>Host-Pathogen Interactions</term>
<term>Immunoblotting</term>
<term>Protein Binding</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Immunotransfert</term>
<term>Interactions hôte-pathogène</term>
<term>Liaison aux protéines</term>
<term>Régulation de l'expression des gènes végétaux</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Pathogenesis-related proteins played a pioneering role 50 years ago in the discovery of plant innate immunity as a set of proteins that accumulated upon pathogen challenge. The most abundant of these proteins, PATHOGENESIS-RELATED 1 (PR-1) encodes a small antimicrobial protein that has become, as a marker of plant immune signaling, one of the most referred to plant proteins. The biochemical activity and mode of action of PR-1 proteins has remained elusive, however. Here, we provide genetic and biochemical evidence for the capacity of PR-1 proteins to bind sterols, and demonstrate that the inhibitory effect on pathogen growth is caused by the sequestration of sterol from pathogens. In support of our findings, sterol-auxotroph pathogens such as the oomycete Phytophthora are particularly sensitive to PR-1, whereas sterol-prototroph fungal pathogens become highly sensitive only when sterol biosynthesis is compromised. Our results are in line with previous findings showing that plants with enhanced PR-1 expression are particularly well protected against oomycete pathogens.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27747953</PMID>
<DateCompleted><Year>2017</Year>
<Month>11</Month>
<Day>21</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>02</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1365-313X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>89</Volume>
<Issue>3</Issue>
<PubDate><Year>2017</Year>
<Month>02</Month>
</PubDate>
</JournalIssue>
<Title>The Plant journal : for cell and molecular biology</Title>
<ISOAbbreviation>Plant J</ISOAbbreviation>
</Journal>
<ArticleTitle>The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein.</ArticleTitle>
<Pagination><MedlinePgn>502-509</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/tpj.13398</ELocationID>
<Abstract><AbstractText>Pathogenesis-related proteins played a pioneering role 50 years ago in the discovery of plant innate immunity as a set of proteins that accumulated upon pathogen challenge. The most abundant of these proteins, PATHOGENESIS-RELATED 1 (PR-1) encodes a small antimicrobial protein that has become, as a marker of plant immune signaling, one of the most referred to plant proteins. The biochemical activity and mode of action of PR-1 proteins has remained elusive, however. Here, we provide genetic and biochemical evidence for the capacity of PR-1 proteins to bind sterols, and demonstrate that the inhibitory effect on pathogen growth is caused by the sequestration of sterol from pathogens. In support of our findings, sterol-auxotroph pathogens such as the oomycete Phytophthora are particularly sensitive to PR-1, whereas sterol-prototroph fungal pathogens become highly sensitive only when sterol biosynthesis is compromised. Our results are in line with previous findings showing that plants with enhanced PR-1 expression are particularly well protected against oomycete pathogens.</AbstractText>
<CopyrightInformation>© 2016 The Authors The Plant Journal © 2016 John Wiley & Sons Ltd.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gamir</LastName>
<ForeName>Jordi</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Darwiche</LastName>
<ForeName>Rabih</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Van't Hof</LastName>
<ForeName>Pieter</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Choudhary</LastName>
<ForeName>Vineet</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Stumpe</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Schneiter</LastName>
<ForeName>Roger</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Mauch</LastName>
<ForeName>Felix</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Biology, University of Fribourg, Fribourg, Switzerland.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2017</Year>
<Month>02</Month>
<Day>01</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Plant J</MedlineTA>
<NlmUniqueID>9207397</NlmUniqueID>
<ISSNLinking>0960-7412</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000890">Anti-Infective Agents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D010940">Plant Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D013261">Sterols</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>97C5T2UQ7J</RegistryNumber>
<NameOfSubstance UI="D002784">Cholesterol</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000890" MajorTopicYN="N">Anti-Infective Agents</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002784" MajorTopicYN="N">Cholesterol</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D060467" MajorTopicYN="N">Disease Resistance</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018506" MajorTopicYN="N">Gene Expression Regulation, Plant</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D054884" MajorTopicYN="N">Host-Pathogen Interactions</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015151" MajorTopicYN="N">Immunoblotting</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018551" MajorTopicYN="N">Lycopersicon esculentum</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010838" MajorTopicYN="N">Phytophthora</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010935" MajorTopicYN="N">Plant Diseases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010940" MajorTopicYN="N">Plant Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010944" MajorTopicYN="N">Plants</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011485" MajorTopicYN="N">Protein Binding</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013261" MajorTopicYN="N">Sterols</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014026" MajorTopicYN="N">Tobacco</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">CAP protein</Keyword>
<Keyword MajorTopicYN="Y">PR-1</Keyword>
<Keyword MajorTopicYN="Y">Phytophthora</Keyword>
<Keyword MajorTopicYN="Y">antimicrobial protein</Keyword>
<Keyword MajorTopicYN="Y">plant immunity</Keyword>
<Keyword MajorTopicYN="Y">sterol binding</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>08</Month>
<Day>18</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2016</Year>
<Month>10</Month>
<Day>11</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>10</Month>
<Day>12</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2016</Year>
<Month>10</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>11</Month>
<Day>29</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2016</Year>
<Month>10</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">27747953</ArticleId>
<ArticleId IdType="doi">10.1111/tpj.13398</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Suisse</li>
</country>
<region><li>Canton de Fribourg</li>
</region>
<settlement><li>Fribourg</li>
</settlement>
<orgName><li>Université de Fribourg</li>
</orgName>
</list>
<tree><country name="Suisse"><region name="Canton de Fribourg"><name sortKey="Gamir, Jordi" sort="Gamir, Jordi" uniqKey="Gamir J" first="Jordi" last="Gamir">Jordi Gamir</name>
</region>
<name sortKey="Choudhary, Vineet" sort="Choudhary, Vineet" uniqKey="Choudhary V" first="Vineet" last="Choudhary">Vineet Choudhary</name>
<name sortKey="Darwiche, Rabih" sort="Darwiche, Rabih" uniqKey="Darwiche R" first="Rabih" last="Darwiche">Rabih Darwiche</name>
<name sortKey="Mauch, Felix" sort="Mauch, Felix" uniqKey="Mauch F" first="Felix" last="Mauch">Felix Mauch</name>
<name sortKey="Schneiter, Roger" sort="Schneiter, Roger" uniqKey="Schneiter R" first="Roger" last="Schneiter">Roger Schneiter</name>
<name sortKey="Stumpe, Michael" sort="Stumpe, Michael" uniqKey="Stumpe M" first="Michael" last="Stumpe">Michael Stumpe</name>
<name sortKey="Van T Hof, Pieter" sort="Van T Hof, Pieter" uniqKey="Van T Hof P" first="Pieter" last="Van'T Hof">Pieter Van'T Hof</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PhytophthoraV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000899 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000899 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Bois
   |area=    PhytophthoraV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:27747953
   |texte=   The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:27747953" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a PhytophthoraV1

This area was generated with Dilib version V0.6.38.
Data generation: Fri Nov 20 11:20:57 2020. Site generation: Wed Mar 6 16:48:20 2024

	Serveur d'exploration Phytophthora
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Phytophthora

The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein.

The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki